Everything
2.15.7.3 Other notes

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No events can be set to local variables.

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Events do not occur during step execution (including return execution) and program execution by selecting [Go to Here] from the context menu.

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If the location set for an existing event changes to midway in an instruction because the program to debug has been downloaded again, re-set the event using the following method.

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If debugging information is available:
The location setting of events is always moved to the beginning of the source text line.

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If debugging information is not available:
Depends on the [Automatic change method of event setting position] property in the [Download] category on the [Download File Settings] tab of the Property panel.

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If a change to internal ROM/RAM changes the location the event is set to a non-mapped area, then set events will not occur (they will also not change to Invalid state /Suspended State on the Events panel).

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If you differentiate function or variable names by leading underscores, then CS+ may misrecognize them, and convert symbols or make break event settings invalid. This applies for cases like when you have two functions, one named "_reset" and the other named "__reset".

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If there is code (text sections) to be ROMified, any software break event set for that code will be deleted during copy to RAM. For this reason, no break will occur.

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For other than [Simulator]
Use a hardware break event.

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[Simulator]
Execution will not break even if a hardware break event is used, but it will break if the trace function or the timer function is valid (on the [Debug Tool Settings] tab of the Property panel, specify [Yes] with the [Use trace function]/[Use timer function] property on the [Trace]/[Timer] category).

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For other than [IECUBE]
If a software break event is set in a boot-swap area, then a break instruction will be written to the flash ROM.
For this reason, a break instruction will remain after the boot swap.

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[E1][E20][EZ Emulator]
Use a hardware break event in a boot-swap area if you wish to.

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[Simulator]
Do not use a break event in a boot-swap area.

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For other than [Simulator]
Hardware Break events with access conditions and Point Trace events [IECUBE] cannot be set for 32-bit (4-byte) variables.
Additionally, Hardware Break events with access conditions and Point Trace events [IECUBE] cannot be detected if a single byte of a 16-bit (2-byte) variable is accessed.